Endocrine Abstracts

Background: Most thyroid nodules are benign, but they can also be associated with thyroid cancer. To be sure how to proceed with an ultrasound suspicious nodule (EU-TIRADS), it is recommended to perform a fine needle aspiration (FNA) biopsy and classify the nodule in the BETHESDA system.Objectives: The aim of this study was to investigate whether we perform an excessive number of FNA according to the EU-TIRADS classification in order to reduce the number...

Background: Hypomagnesemia is an electrolyte disturbance defined by a low serum magnesium level. Causes of hypomagnesemia include inadequate dietary intake, decreased intestinal absorption, and increased renal excretion. The clinical presentation varies depending on the severity of the magnesium deficiency-from asymptomatic cases to patients with mild symptoms, to severe, life-threatening cardiac arrhythmias and seizures.Case presentation: A 55-year-old ...

Background: The increasing prevalence of diabetes mellitus (DM) is leading to a higher number of patients with diabetic retinopathy (DR) being referred to an ophthalmologist. In order to provide better care for patients, the Department of Endocrinology at the University Hospital of Zagreb has started screening of the ocular fundus.Objectives: The aim was to present the results of screening on DR in a random sample of DM patients and to compare the result...

Background: Adrenal venous sampling (AVS) is the gold standard to differentiate patients with unilateral primary aldosteronism (UPA) from those with bilateral disease (BPA).Objective: The aim of this study was to evaluate the efficiency of using the online Integer scoring system in predicting BPA, as a possible surrogate for AVS.Methods: We performed a retrospective analysis of 105 patients (66 female, median age at diagnosis 53 ye...

Background: Adrenal venous sampling (AVS) is considered the gold standard for differentiating an aldosterone- producing adenoma (aPA) from bilateral adrenal hyperplasia (BAH).Objective: The aim of this study is to present our experience with this method in our hospital.Methods: We performed a retrospective analysis of 105 patients who underwent the AVS protocol at our centre between 2015 and 2022 for PA.Resul...

Introduction: Mitotane is an adrenolytic drug which is used in patients with adrenocortical carcinoma (ACC) and leads to adrenal insufficiency (AI). The aim of this study was to evaluate the time to recovery of the hypothalamus-pituitary-adrenal (HPA) axis after adjuvant mitotane treatment and to determine possible predictive factors.Materials and Methods: In this retrospective study, we included 19 patients with ACC, ENSAT stage I- III, who were treated...